产品关键词 Nonactin
Ammonium ionophore
无活菌素
产品介绍 | 经验分子式(希尔表示法) | C40H64O12 | | 分子量 | 736.93 | | Beilstein Registry Number【贝尔斯坦登记号】 | 76434 | | EINECS 编号【欧洲现有商业化学物质名录编号】 | 229-911-3 | | PubChem Substance ID【PubChem数据库物质ID】 | 24886652 | | General description【一般说明】 | may contain the homologues monactin and dinactin | | Other Notes【其它说明】 | Natural macrotetrolide | | Application【应用】 | Nonactin is used as a neutral lipid membrane soluble ammonium (and potassium) ionophore, as an uncoupler of oxidative phosphorylation, and to inhibit surface expression of certain heat shock proteins (HSP60) . | | Biochem/physiol Actions【生物化学/生理学作用】 | Nonactin is a macrotetrolide that forms complexes with alkali cations, such as potassium and sodium. Nonactin has been reported to inhibit the processing of cytoplasmic precursor proteins destined for the mitochondria. Nonactin is a uncoupler of oxidative phosphorylation . |
产品性质 | biological source【生物源】 | from Streptomyces sp. | | Assay【含量】 | ≥97.0% (TLC) | | Mode of action | DNA synthesis | interferescell membrane | interferesenzyme | inhibits | | antibiotic activity spectrum【抗菌活性谱】 | Gram-positive bacteria | | storage temp.【存储温度】 | 2-8℃ |
安全信息 | 个人防护装备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter | | RIDADR【欧洲内陆运输危险品】 | NONH for all modes of transport | | WGK德国【德国水污染分类】 | 3 | | RTECS【化学物质毒性作用登记号】 | RH1685000 |
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