Catalog Number

KMH686

Product Name

Recombinant Human ApolipoProtein E/APOE Protein, His Tag

Alias

AD2, LPG, APO-E, ApoE4, LDLCQ5, apolipoprotein E

Size

50μg, 100μg

Species

Human

Host

Mammalian Cells

Source

This protein contains the human APOE(Lys19-His317) was fused with the

C-terminal His Tag and expressed in Mammalian cells.

Uniprot Accession

P02649

Purity

≥90% as determined by SDS-PAGE

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Buffer

PBS

Predicted Molecular

Weight

32.89kDa

Background

The protein encoded by this gene is a major apoprotein of the chylomicron. It

binds to a specific liver and peripheral cell receptor, and is essential for the

normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps

to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes.

Mutations in this gene result in familial dysbetalipoproteinemia, or type III

hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and

triglycerides are the consequence of impaired clearance of chylomicron and

VLDL remnants. Alternative splicing results in multiple transcript variants.

Storage

Store the product under sterile conditions after opening at -20℃ to -80℃ for 12

months. Avoid repeated freeze-thaw cycles.

Shipping Condition

This product is shipped on ice packs or dry ice.

For Research Use Only