GNF 5837

CAS NO:1033769-28-6
规格:≥98% (HPLC)
包装规格:5 MG,25 MG,10 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3091803Sigma-Aldrich5 MG1920请咨询
3091803Sigma-Aldrich25 MG5640请咨询
4170029Sigma-Aldrich10 MG4130请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C28H21F4N5O2
Molecular weight
535.49
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
GNF-5837 is an orally bioavailable Trk inhibitor (IC50 = 8 and 12 nM for TrkA and TrkB, respectively). GNF-5837 inhibits growth of Ba/F3 cells expressing Tel-Trl fusions. IC50 values for growth inhibition are Tel-TrkA = 11 nM, Tel-TrkB = 9 nM and Tel-TrkC = 7 nM.
Features and Benefits【特点和优势】
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
yellow to orange
solubility【溶解性】
DMSO: 5 mg/mL, clear (warmed)
storage temp.【储存温度】
2-8℃
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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