H-7 dihydrochloride

CAS NO:108930-17-2
规格:≥98% (HPLC)
包装规格:5 MG,25 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3094273Sigma-Aldrich5 MG2930请咨询
3094273Sigma-Aldrich25 MG7230请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H17N3O2S · 2HCl
Molecular weight
364.29
Beilstein
5840763
MDL number
MFCD00036961
PubChem Substance ID【PubChem化学物质编号】
24278496
NACRES
NA.77
General description【一般描述】
H-7 dihydrochloride blocks human immunodeficiency virus (HIV-1) replication in MOLT-4 (clone No. 8) cell line. It increases the secretion of interleukin 1β (IL-1β).
Application【应用】
H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.
Biochem/physiol Actions【生化/生理作用】
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.
Caution【注意】
Light sensitive
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥98% (HPLC)
form【形式】
powder
solubility【溶解性】
H2O: 20 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Cl.Cl.CC1CNCCN1S(=O)(=O)c2cccc3cnccc23
InChI
1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H
InChI key
OARGPFMFRLLKPF-UHFFFAOYSA-N
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
packaging【包装】
5 mg in glass bottle
25 mg in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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