Eicosapentaenoyl ethanolamide
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3080772 | Sigma-Aldrich | 5 MG | 1320 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C22H35NO2 |
| Molecular weight | 345.52 |
| MDL number | MFCD22416528 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825384 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Eicosapentaenoyl ethanolamide (EPEA) is a lipid mediator that has been found to suppress lifespan extension resulting from dietary restriction in C. elegans and also to have antiproliferative and anti-inflammatory actions. In C. elegans, it is believed to act as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA is a member of the N-acylethanolamines (NAEs), lipid-derived signaling molecules that include the mammalian endocannabinoid arachidonoyl ethanolamide (AEA). In mammals, NAEs are believed to act primarily through cannabinoid receptors, although they can also interact with a variety of other targets, and EPEA has been shown to act as a CB1 and CB2 receptor agonist. However, C. elegans does not possess clear orthologues of the mammalian cannabinoid receptors which suggests that there are unidentified NAE receptors in nematodes that are possibly conserved mediators of NAE signaling. |
| Other Notes【其他说明】 | Light and air sensitive; store in a freezer. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solution |
| drug control | regulated under CDSA - not available from sigma-aldrich Canada |
| storage condition【储存条件】 | protect from light under inert gas |
| concentration【浓度】 | 5 mg/mL in absolute ethanol |
| color【颜色】 | light yellow |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO |
| InChI | 1S/C22H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h3-4,6-7,9-10,12-13,15-16,24H,2,5,8,11,14,17-21H2,1H3,(H,23,25)/b4-3-,7-6-,10-9-,13-12-,16-15- |
| InChI key | OVKKNJPJQKTXIT-JLNKQSITSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |