产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3190625 | Sigma-Aldrich | 5 MG | 2180 | 请咨询 |
| 4009597 | J&K | 10MG | 914 | 请咨询 |
| 4009597 | J&K | 50MG | 3100 | 请咨询 |
| 4084143 | Sigma-Aldrich | 5 MG | 2570 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C17H17N7 |
| Molecular weight | 319.36 |
| MDL number | MFCD12912434 |
| PubChem Substance ID【PubChem化学物质编号】 | 329819987 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases. PP121 blocks the vascular endothelial growth factor (VEGF) receptor and its related signaling events. It also inhibits tumor cell proliferation by targeting oncogenic tyrosine kinase and phosphoinositide 3-kinases (PI3Ks). |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C5CCCC5 |
| InChI | 1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22) |
| InChI key | NVRXTLZYXZNATH-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 1 |