Ouabain, Octahydrate-CAS 11018-89-6-Calbiochem

CAS NO:11018-89-6
规格:Inhibits Na+,K+-ATPase.
包装规格:1 G
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产品价格
产品编号品牌包装单位单价(元)现货
4061771Sigma-Aldrich1 G2150请咨询
基本信息
Empirical Formula【经验(实验)分子式】
C29H44O12 · 8H2O
Molecular weight
728.77
MDL number
MFCD00149240
NACRES
NA.77
General description【一般描述】
Inhibits Na+ and K+-dependent ATPases. Has cardiotonic properties.
Inhibits Na+,K+-ATPase. Exhibits cardiotonic properties. Preferentially enhances radiotoxicity in tumor cells and induces apoptosis by prolonging the irradiation-induced G2 delay.
Biochem/physiol Actions【生化/生理作用】
Primary Target
Na+,K+-ATPase
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Warning【警告】
Toxicity: Toxic (F)
Reconstitution【重悬】
Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 2 months at -20°C.
Other Notes【其他说明】
Verheye-Dua, F.A., and Bohm, L. 2000. Strahlenther Onkol. 176, 186.
Hasenauer, J., et al. 1993. J. Biol. Chem.268, 3289.
Rakowski, F.F. 1993. J. Gen. Physiol.101, 117.
Mahaney, J.E., and Grisham, C.M. 1992. Biochemistry31, 2025.
Xu, Z.J., et al. 1992. J. Physiol.456, 405.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Legal Information【法律信息】
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
solid
manufacturer/tradename
Calbiochem®
storage condition【储存条件】
OK to freeze
protect from light
color【颜色】
white to off-white
solubility【溶解性】
hot water: 10 mg/mL
room-temperature water: insoluble
shipped in【运输】
ambient
storage temp.【储存温度】
2-8℃
InChI
1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13?,15-,16+,17?,18+,19+,21+,22?,23?,24?,25?,26?,27?,28?,29?;;;;;;;;/m0......../s1
InChI key
TYBARJRCFHUHSN-HMNHGHQSSA-N
packaging【包装】
1 g in Glass bottle
安全信息
Pictograms【象形图】
GHS06,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H300 - H331 - H373
Precautionary Statements
P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314
Hazard Classifications【危险分类】
Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2
Storage Class Code【储存分类代码】
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
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