R-(-)-Fluoxetine hydrochloride

C₁₇H₁₈NOF₃ · HCl

345.79

MFCD04040065

24278433

NA.77

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

• to study its effects on the embryoid body (EB) morphogenesis
• in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
• to study its effects as an endocrine disruption inducer in Pimephales promelas

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.
Selective serotonin reuptake inhibitor.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

100

>98% (HPLC)

solid

white

H₂O: soluble >10 mg/mL

Eli Lilly

Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1

GIYXAJPCNFJEHY-PKLMIRHRSA-N

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

5, 25 mg in glass bottle

GHS05,GHS07

Danger

H302 - H315 - H318

P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

11 - Combustible Solids

WGK 3

dust mask type N95 (US), Eyeshields, Gloves