QNZ46

CAS NO:1237744-13-6
规格:≥98% (HPLC)
包装规格:25 MG,5 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3212757Sigma-Aldrich25 MG4770请咨询
3212757Sigma-Aldrich5 MG1710请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C24H17N3O6
Molecular weight
443.41
MDL number
MFCD22666391
PubChem Substance ID【PubChem化学物质编号】
329825390
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
QNZ46 is a noncompetitive inhibitor of GluN2C/D containing NMDA receptors. KD and IC50 values for binding and inhibition of GluN1/Glun2D receptors by QNZ46 are 4.9 and 3.9 μM, respectively. QNZ46 does not compete for binding of glutamate or glycine, but QNZ46 receptor binding requires the binding of glutamate to the GluN2 subunit.
Features and Benefits【特点和优势】
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 5 mg/mL (warmed; clear solution)
storage temp.【储存温度】
room temp
SMILES string
COc1ccc2N=C(\C=C\c3cccc(c3)[N+]([O-])=O)N(C(=O)c2c1)c4ccc(cc4)C(O)=O
InChI
1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+
InChI key
GNLVJIICVWDSNI-LFYBBSHMSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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