雷莫司琼 盐酸盐
Ramosetron hydrochloride
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3213769 | Sigma-Aldrich | 10 MG | 968 | 请咨询 |
| 3213769 | Sigma-Aldrich | 50 MG | 3410 | 请咨询 |
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H17N3O · HCl |
| Molecular weight | 315.80 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ramosetron is a tetra hydrobenzimidazole derivative, containing an indole ring. It inhibits colon contraction mediated by serotonin, competitively. Ramosetron hydrochloride is a potent serotonin 5-HT3 receptor antagonist with higher afinity for the 5-HT3 receptor than other currently available antagonists. Ramosetron is used clinically both as an antiemetic to treat nausea and vomiting following chemotherapy or after surgery, and in treatment of irritable bowel syndrome. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -40 to -45°, c = 1 in methanol |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 20 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1 |
| InChI key | XIXYTCLDXQRHJO-RFVHGSKJSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |