SB 205384
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3216979 | Sigma-Aldrich | 5 MG | 2680 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C17H18N2O3S |
| Molecular weight | 330.40 |
| MDL number | MFCD00918851 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278711 |
| NACRES | NA.77 |
| Application【应用】 | SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6 |
| Biochem/physiol Actions【生化/生理作用】 | SB 205384 is a selective and positive allosteric modulator of non-benzodiazepine site of the GABAA receptor.3 It affects the extrasynaptic GABAA receptors in rat cortical neurons4 and enhances the GABAergic transmission onto pro-opiomelanocortin neurons in mice.5 GABAA receptor modulator selective for the α3β2γ2 subunit combination. |
| Legal Information【法律信息】 | Manufactured and sold under license from GlaxoSmithKline Pharmaceuticals |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: 18 mg/mL H2O: insoluble |
| SMILES string | CC#CCOC(=O)c1c(C)nc2sc3CC(O)CCc3c2c1N |
| InChI | 1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19) |
| InChI key | JDTZAGLGBRRCJT-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |