Fluspirilene

CAS NO:1841-19-6
包装规格:10 MG,50 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3088218Sigma-Aldrich10 MG2310请咨询
3088218Sigma-Aldrich50 MG6710请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C29H31F2N3O
Molecular weight
475.57
EC number【EC 号】
217-418-6
MDL number
MFCD00055137
PubChem Substance ID【PubChem化学物质编号】
24277915
NACRES
NA.77
Application【应用】
Fluspirilene has been used as a neuroleptic drug to study its effects on human ether-a-go-go related gene (HERG).
Fluspirilene has been used to study its cytotoxicity effect on malignant glioma.
Biochem/physiol Actions【生化/生理作用】
Fluspirilene has a potential to inhibit the activity of cyclin-dependent kinase 2 (CDK2). It is an effective anti-cancer agent used for treating human hepatocellular carcinoma.
Fluspirilene is a dopamine receptor antagonist. It also acts as a calcium channel blocker. Fluspirilene is an antipsychotic agent and exhibits neuoleptic properties. It exhibits therapeutic effects against glioblastoma and Schizophrenia.
Features and Benefits【特点和优势】
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
solid
color【颜色】
white
solubility【溶解性】
DMSO: ≥20 mg/mL
H2O: insoluble
ethanol: soluble
originator【创始人】
Johnson & Johnson
storage temp.【储存温度】
room temp
SMILES string
Fc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5
InChI
1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)
InChI key
QOYHHIBFXOOADH-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
packaging【包装】
10, 50 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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