Dilazep dihydrochloride

CAS NO:20153-98-4
规格:powder
包装规格:50 MG,100 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3077381Sigma-Aldrich50 MG3240请咨询
3077381Sigma-Aldrich100 MG5530请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C31H44N2O10 · 2HCl
Molecular weight
677.61
EC number【EC 号】
243-548-8
MDL number
MFCD00133267
PubChem Substance ID【PubChem化学物质编号】
24278372
NACRES
NA.77
General description【一般描述】
Dilazep comprises central cyclic diamine and phenyl rings connected via alkyl linkers.
Application【应用】
Dilazep dihydrochloride has been used in estrogen receptor (ERα) antagonistic assay. It has also been used as an equilibrative nucleoside transporter inhibitor (ENT 1 and 2) in cancer cell lines.
Biochem/physiol Actions【生化/生理作用】
Dilazep is a equilibrative nucleoside transporter 1 (ENTs) inhibitor. It is an antianginal drug and an effective coronary vasodilator. Dilazep elicits anti-albuminuric effects and is an anti-platelet agent. It is a potent adenosine uptake inhibitor and suppresses effects of ischemia.
产品性质
form【形式】
powder
Quality Level【质量水平】
200
color【颜色】
white
solubility【溶解性】
H2O: 10 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Cl[H].Cl[H].COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2
InChI
1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H
InChI key
VILIWRRWAWKXRW-UHFFFAOYSA-N
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
packaging【包装】
100 mg in glass bottle
50 mg in poly bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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