FH1

CAS NO:2719-05-3
规格:≥98% (HPLC)
包装规格:5 MG,25 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3087222Sigma-Aldrich5 MG840请咨询
3087222Sigma-Aldrich25 MG3100请咨询
基本信息
Empirical Formula【经验(实验)分子式】
C17H18N2O2
Molecular weight
282.34
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
FH1 (BRD-K4477) was found to enhance hepatocyte functions and promote the differentiation of induced pluripotent stem cell–derived hepatocytes toward a more mature phenotype than what had previouslybeen obtainable. Human induced pluripotent stem (iPS) cells that are differentiated toward hepatocyte-like (iHep) cells typically show an immature hepatic phenotype and have limited use as a renewable source of functional human hepatocytes. Cultures treated with both FH1 (BRD-K4477) and another compound that induces proliferation, FPH1 (BRD-6125), contained larger colonies of iHep cells, which showed more pronounced hepatocyte morphologies with a more mature phenotype than previously obtainable.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 10 mg/mL, clear (warmed)
storage temp.【储存温度】
2-8℃
InChI
1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21)
InChI key
OEXMNSOPAKOPEF-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS09
Signal word【警示用语:】
Warning
Hazard Statements
H400
Precautionary Statements
P273
Hazard Classifications【危险分类】
Aquatic Acute 1
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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