IMB-10

CAS NO:307525-40-2
规格:≥98% (HPLC)
包装规格:5 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3098395Sigma-Aldrich5 MG1550请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H15NOS2
Molecular weight
337.46
MDL number
MFCD20134199
PubChem Substance ID【PubChem化学物质编号】
329825094
NACRES
NA.77
Application【应用】
IMB-10 may be used to study integrin-mediated signaling in tumor cells.
Biochem/physiol Actions【生化/生理作用】
IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
yellow
solubility【溶解性】
DMSO: ≥25 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Cc1ccccc1N2C(=S)S\C(=C\C=C\c3ccccc3)C2=O
InChI
1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+
InChI key
UYZLENPCNZVWQZ-QHMSGILQSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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