PRT4165

CAS NO:31083-55-3
规格:≥98% (HPLC)
包装规格:25 MG,5 MG,1 G,10MG,5MG,1g,250mg
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产品价格
产品编号品牌包装单位单价(元)现货
3208854Sigma-Aldrich25 MG3940请咨询
3208854Sigma-Aldrich5 MG1120请咨询
3219749Sigma-Aldrich1 G17180请咨询
4007482J&K10MG710请咨询
4007482J&K5MG513请咨询
4178623Fluorochem1g19290请咨询
4178623Fluorochem250mg7740请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H9NO2
Molecular weight
235.24
MDL number
MFCD00435709
PubChem Substance ID【PubChem化学物质编号】
329825631
Biochem/physiol Actions【生化/生理作用】
PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX.
Features and Benefits【特点和优势】
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 20 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
O=C1C(C(C2=C1C=CC=C2)=O)=CC3=CN=CC=C3
InChI
1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H
InChI key
OMHZFEWYVFWVLI-UHFFFAOYSA-N
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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