Febrifugine dihydrochloride
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3086892 | Sigma-Aldrich | 5 MG | 1840 | 请咨询 |
| 3086892 | Sigma-Aldrich | 25 MG | 6760 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C16H19N3O3 · 2HCl |
| Molecular weight | 374.26 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825583 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity. Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inhibitor of prolyl-transfer RNA synthetase (ProRS). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D 10 to 15°, c = 1 in H2O |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | off-white to gray-brown |
| solubility【溶解性】 | H2O: 15 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C1C2=CC=CC=C2N=CN1CC(C[C@@H]3[C@@H](O)CCCC3)=O.C |
| InChI | 1S/C17H20N2O3.CH4/c20-13(9-12-5-1-4-8-16(12)21)10-19-11-18-15-7-3-2-6-14(15)17(19)22;/h2-3,6-7,11-12,16,21H,1,4-5,8-10H2;1H4/t12-,16+;/m1./s1 |
| InChI key | SNTOTCUGCWLHEZ-KKJWGQAZSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |