ITX3

CAS NO:347323-96-0
规格:≥98% (HPLC)
包装规格:5 MG,25 MG,10 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3101991Sigma-Aldrich5 MG1140请咨询
3101991Sigma-Aldrich25 MG3810请咨询
4170021Sigma-Aldrich10 MG2150请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H17N3OS
Molecular weight
371.45
MDL number
MFCD02629172
PubChem Substance ID【PubChem化学物质编号】
329815351
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs.
Features and Benefits【特点和优势】
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
solubility【溶解性】
DMSO: ≥4 mg/mL
storage temp.【储存温度】
room temp
SMILES string
Cc1cc(\C=C2\Sc3nc4ccccc4n3C2=O)c(C)n1-c5ccccc5
InChI
1S/C22H17N3OS/c1-14-12-16(15(2)24(14)17-8-4-3-5-9-17)13-20-21(26)25-19-11-7-6-10-18(19)23-22(25)27-20/h3-13H,1-2H3/b20-13+
InChI key
SJMYMKPBODEZSH-DEDYPNTBSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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