Procarbazine hydrochloride

CAS NO:366-70-1
规格:,≥98.0%
包装规格:10 MG,50 MG,1g,5g,100MG,500MG,200 MG
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产品价格
产品编号品牌纯度规格包装单位单价(元)现货
3208186Sigma-Aldrich≥98% (HPLC)10 MG1101请咨询
3208186Sigma-Aldrich≥98% (HPLC)50 MG3860请咨询
3465569翁江≥98.0%1g575请咨询
3465569翁江≥98.0%5g1650请咨询
4006032TCI≥98% (HPLC)100MG172请咨询
4006032TCI≥98% (HPLC)500MG588请咨询
4139959USP≥98% (HPLC)200 MG3230请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C12H19N3O·HCl
Molecular weight
257.76
EC number【EC 号】
206-678-6
MDL number
MFCD00072082
PubChem Substance ID【PubChem化学物质编号】
329825106
NACRES
NA.77
Application【应用】
Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer agent. It may be used to study new combination of anticancer drugs.
Procarbazine hydrochloride has been used to study its physicochemical property.
Biochem/physiol Actions【生化/生理作用】
Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.
Procarbazine is metabolized to azoprocarbazine either by cytochrome P450 enzyme and monoamine oxidase in an NADPH (nicotinamide adenine diphosphate) dependent or independent manner. It is considered neurotoxic. Procarbazine is used in combination with therapy for treating Hodgkin′s disease.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to tan
solubility【溶解性】
DMSO: ≥18 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Cl.CNNCc1ccc(cc1)C(=O)NC(C)C
InChI
1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
InChI key
DERJYEZSLHIUKF-UHFFFAOYSA-N
packaging【包装】
10, 50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H302 - H341 - H350 - H360
Precautionary Statements
P201 - P301 + P312 + P330 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1A
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
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