SB-366791

CAS NO:472981-92-3
规格:≥98% (HPLC), powder
包装规格:25 MG,5 MG,100MG,25MG,5MG
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产品价格
产品编号品牌包装单位单价(元)现货
3217005Sigma-Aldrich25 MG7700请咨询
3217005Sigma-Aldrich5 MG2650请咨询
4003547TCI100MG1920请咨询
4003547TCI25MG540请咨询
4013034J&K25MG1360请咨询
4013034J&K5MG518请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C16H14NO2Cl
Molecular weight
287.74
MDL number
MFCD01033818
PubChem Substance ID【PubChem化学物质编号】
24278690
NACRES
NA.77
Application【应用】
SB-366791 has been used as a transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist:
  • to infer the in vitro and in vivo pharmacology of (E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide (AMG 9810)
  • to study its effects on sodium hydrogen sulfide (NaHS) or capsaicin-induced contractile activity
  • to study the inhibitory potency of phoneutria toxin (PnTx3-5) (native and recombinant) on various responses mediated by transient receptor potential cation channel subfamily V member 1 (TRPV1)

Biochem/physiol Actions【生化/生理作用】
SB-366791 might exhibit analgesic properties on bone cancer-related pain behavior.
Vanilloid receptor-1 (TRPV1) antagonist.
Features and Benefits【特点和优势】
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 5 mg/mL, clear
originator【创始人】
GlaxoSmithKline
SMILES string
COc1cccc(NC(=O)\C=C\c2ccc(Cl)cc2)c1
InChI
1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
InChI key
RYAMDQKWNKKFHD-JXMROGBWSA-N
Gene Information
human ... TRPV1(7442)
packaging【包装】
5 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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