SB 657510
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3216990 | Sigma-Aldrich | 25 MG | 5970 | 请咨询 |
| 3216990 | Sigma-Aldrich | 5 MG | 1640 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C19H22BrClN2O5S |
| Molecular weight | 505.81 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824581 |
| NACRES | NA.77 |
| Application【应用】 | SB 657510 may be used to study the urotensin II receptor-mediated signaling. |
| Biochem/physiol Actions【生化/生理作用】 | SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes.1 SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension. |
| Features and Benefits【特点和优势】 | This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: ≥30 mg/mL |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | room temp |
| SMILES string | COc1cc(Br)c(cc1OC)S(=O)(=O)Nc2ccc(Cl)c(O[C@@H]3CCN(C)C3)c2 |
| InChI | 1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1 |
| InChI key | KQCZCINJGIRLCD-CYBMUJFWSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |