Begacestat
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3094029 | Sigma-Aldrich | 5 MG | 1390 | 请咨询 |
| 3094029 | Sigma-Aldrich | 25 MG | 4860 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C9H8ClF6NO3S2 |
| Molecular weight | 391.74 |
| MDL number | MFCD18782675 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823761 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Begacestat (GSI-953) is a selective γ-secretase inhibitor that selectively inhibits cleavage of APP over Notch. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥15 mg/mL |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC[C@@H](NS(=O)(=O)c1ccc(Cl)s1)C(C(F)(F)F)C(F)(F)F |
| InChI | 1S/C9H8ClF6NO3S2/c10-5-1-2-6(21-5)22(19,20)17-4(3-18)7(8(11,12)13)9(14,15)16/h1-2,4,7,17-18H,3H2/t4-/m1/s1 |
| InChI key | PSXOKXJMVRSARX-SCSAIBSYSA-N |
| Gene Information | human ... APH1A(51107), APH1B(83464), NCSTN(23385), PSEN1(5663), PSEN2(5664), PSENEN(55851) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |