IN-1130
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3098638 | Sigma-Aldrich | 5 MG | 1530 | 请咨询 |
| 3098638 | Sigma-Aldrich | 25 MG | 5640 | 请咨询 |
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H20N6O |
| Molecular weight | 420.47 |
| Biochem/physiol Actions【生化/生理作用】 | IN-1130 is a potent inhibitor of the activin receptor-like kinase ALK-5 (Type 1 TGF1β recptor). The compound inhibits phosphorylation of Smad-2 with an IC50 of 36 nM. IN-1130 inhibits renal fibrosis, and also reduces tumor volume in prostate tumor xenografts in murine models. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |