Ro 15-4513

CAS NO:91917-65-6
规格:solid
包装规格:100 MG,25 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3215589Sigma-Aldrich100 MG20040请咨询
3215589Sigma-Aldrich25 MG5930请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H14N6O3
Molecular weight
326.31
MDL number
MFCD00078598
PubChem Substance ID【PubChem化学物质编号】
24899343
Application【应用】
Ro 15-4513 has been used as a benzodiazepine (Bz) inverse agonist in rats and to test its binding with diazepam-sensitive (DS) receptors in in vitro radioligand binding studies.
Biochem/physiol Actions【生化/生理作用】
Ro 15-4513 is benzodiazepine receptor partial inverse agonist. It elicits anxiogenic property and is an ethanol antagonist. It elicits a high affinity towards diazepam sensitive and insensitive sites in the cerebellar region. Ro 15-4513 possesses an imidazo ring and is an imidazobenzodiazepine.
Features and Benefits【特点和优势】
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
100
form【形式】
solid
color【颜色】
tan
solubility【溶解性】
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL
H2O: insoluble
methanol: soluble
originator【创始人】
Roche
SMILES string
CCOC(=O)c1ncn-2c1CN(C)C(=O)c3cc(ccc-23)N=[N+]=[N-]
InChI
1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChI key
CFSOJZTUTOQNIA-UHFFFAOYSA-N
Gene Information
human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559)
rat ... Gabrg1(140674)
packaging【包装】
25, 100 mg in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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