KC7F2

CAS NO:927822-86-4
规格:≥98% (HPLC)
包装规格:1 MG,5 MG,5MG,10MG,25 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3102482Sigma-Aldrich1 MG645请咨询
3102482Sigma-Aldrich5 MG995请咨询
4007212J&K5MG513请咨询
4007212J&K10MG710请咨询
4157324Sigma-Aldrich25 MG3130请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C16H16Cl4N2O4S4
Molecular weight
570.38
MDL number
MFCD22683809
PubChem Substance ID【PubChem化学物质编号】
329825637
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
KC7F2 is a cell permeable potent HIF-1 pathway inhibitor. KC7F2 inhibits the activation of HIF-target genes such as carbonic anhydrase IX, matrix metalloproteinase 2 (MMP2), enolase 1, and endothelin 1. KC7F2 suppresses the protein accumulation of HIF-1? in cancer cell lines by inhibition of its protein synthesis at the translation level. KC7F2 is preferentially cytotoxicity to cancer cells, an effect that is increased in hypoxia.
Features and Benefits【特点和优势】
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Other Notes【其他说明】
air sensitive
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 20 mg/mL, clear
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
SMILES string
ClC1=CC=C(Cl)C=C1S(NCCSSCCNS(C2=C(Cl)C=CC(Cl)=C2)(=O)=O)(=O)=O
InChI
1S/C16H16Cl4N2O4S4/c17-11-1-3-13(19)15(9-11)29(23,24)21-5-7-27-28-8-6-22-30(25,26)16-10-12(18)2-4-14(16)20/h1-4,9-10,21-22H,5-8H2
InChI key
REQLACDIZMLXIC-UHFFFAOYSA-N
packaging【包装】
1, 5 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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