Fmoc-(R)-2-(7-octenyl)Ala-OH

CAS NO:945212-26-0
包装规格:1 G,5 G,100MG,250MG,500MG,1G
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产品价格
产品编号品牌包装单位单价(元)现货
3088428Sigma-Aldrich1 G2180请咨询
3088428Sigma-Aldrich5 G9450请咨询
3513480J&K100MG1180请咨询
3513480J&K250MG1330请咨询
3513480J&K500MG2410请咨询
3513480J&K1G3980请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C26H31NO4
Molecular weight
421.53
MDL number
MFCD12925761
PubChem Substance ID【PubChem化学物质编号】
329799756
NACRES
NA.26
Application【应用】
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
产品性质
Quality Level【质量水平】
200
form【形式】
solid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group【官能团】
Fmoc
storage temp.【储存温度】
−20℃
SMILES string
O=C(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)N[C@@](CCCCCCC=C)(C)C(O)=O
InChI
1S/C26H31NO4/c1-3-4-5-6-7-12-17-26(2,24(28)29)27-25(30)31-18-23-21-15-10-8-13-19(21)20-14-9-11-16-22(20)23/h3,8-11,13-16,23H,1,4-7,12,17-18H2,2H3,(H,27,30)(H,28,29)/t26-/m1/s1
InChI key
MADFVGMQNXRFAF-AREMUKBSSA-N
packaging【包装】
1, 5 g in glass bottle
安全信息
Pictograms【象形图】
GHS09
Signal word【警示用语:】
Warning
Hazard Statements
H400
Precautionary Statements
P273
Hazard Classifications【危险分类】
Aquatic Acute 1
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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