DMH2
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3079239 | Sigma-Aldrich | 5 MG | 1530 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C27H25N5O2 |
| Molecular weight | 451.52 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825950 |
| General description【一般描述】 | DMH2 is a small molecule, which has ability to inhibit BMP type I receptors. The bone morphogenetic proteins (BMP) signal inhibition further decreases expression of Id proteins in lung cells. |
| Biochem/physiol Actions【生化/生理作用】 | DMH2 is a potent antagonist of the BMP receptor activin receptor-like kinase 3 (ALK3, BMPR-IA) that enhance liver regeneration. DMH2 potently inhibits BMP signaling and induced the greatest reduction of cell growth and expression of Id family members in H1299 non-small cell lung carcinoma cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 1 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | N1(CCOC2=CC=C(C(C=N3)=CN4C3=C(C5=CC=NC6=C5C=CC=C6)C=N4)C=C2)CCOCC1 |
| InChI | 1S/C27H25N5O2/c1-2-4-26-24(3-1)23(9-10-28-26)25-18-30-32-19-21(17-29-27(25)32)20-5-7-22(8-6-20)34-16-13-31-11-14-33-15-12-31/h1-10,17-19H,11-16H2 |
| InChI key | DXLXRNZCYAYUED-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |