Mastoparan-7

CAS NO:145854-59-7
规格:≥97% (HPLC), lyophilized powder
包装规格:1 MG,1 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3108049Sigma-Aldrich1 MG2670请咨询
4061712Sigma-Aldrich1 MG2540请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C67H124N18O15
Molecular weight
1421.81
MDL number
MFCD00144726
PubChem Substance ID【PubChem化学物质编号】
329817929
NACRES
NA.77
Amino Acid Sequence
Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2
General description【一般描述】
Mastoparan-7 is an analog of the mastoparan peptide. It is present in the venom of Vespula lewisii. It was originally isolated from wasp venom.
Application【应用】
Mastoparan-7 has been used to study mastoparan-stimulated nucleotide binding to G proteins.
Biochem/physiol Actions【生化/生理作用】
Mastoparan-7 (Mas-7) stimulates the G protein subunit Gαo/i by its mode of action (to bind to the plasma membrane). It possesses antiviral activity and is associated with histamine release from mast cells. It is also involved in the induction of potent mitochondrial permeability and tumor cell cytotoxicity.
Analysis Note【分析说明】
More potent analog of mastoparan.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥97% (HPLC)
form【形式】
lyophilized powder
storage temp.【储存温度】
−20℃
SMILES string
CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
InChI
1S/C67H124N18O15/c1-18-38(12)53(71)67(100)85-51(32-52(70)86)66(99)84-50(31-37(10)11)64(97)79-45(24-20-22-26-69)61(94)75-42(16)58(91)82-47(28-34(4)5)62(95)76-39(13)55(88)73-40(14)57(90)81-48(29-35(6)7)63(96)77-41(15)56(89)78-44(23-19-21-25-68)60(93)74-43(17)59(92)83-49(30-36(8)9)65(98)80-46(54(72)87)27-33(2)3/h33-51,53H,18-32,68-69,71H2,1-17H3,(H2,70,86)(H2,72,87)(H,73,88)(H,74,93)(H,75,94)(H,76,95)(H,77,96)(H,78,89)(H,79,97)(H,80,98)(H,81,90)(H,82,91)(H,83,92)(H,84,99)(H,85,100)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-/m0/s1
InChI key
HOLQXBRPSSZJMZ-FGRXCANLSA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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