O-苯甲基磷酸酯-N-Fmoc-L-丝氨酸

O-Benzylphospho-N-Fmoc-L-serine
CAS NO:158171-14-3
规格:,95%
包装规格:250mg,1g,5g,10g,5 G
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结构式
基本信息
应用
It can be applied in the synthesis of phosphopeptides. This derivative can be introduced using standard activation methods, such as PyBOP and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step .
备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
MDL
MFCD00797869
分子式
C25H24NO8P
分子量
497.44
灵敏度
Ambient temperatures.
形态
Powder
溶解性
Slightly soluble in water.
Beilstein
7060483
安全信息
TSCA
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