NNGH

CAS NO:161314-17-6
规格:≥98% (HPLC)
包装规格:25 MG,5 MG,5 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3175613Sigma-Aldrich25 MG4090请咨询
3175613Sigma-Aldrich5 MG1110请咨询
4083906Sigma-Aldrich5 MG2300请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C13H20N2O5S
Molecular weight
316.37
MDL number
MFCD02179370
PubChem Substance ID【PubChem化学物质编号】
329825565
Biochem/physiol Actions【生化/生理作用】
NNGH is a potent and cell-permeable inhibitor of matrix metalloproteinase 3 (MMP-3,stromelysin 1, progelatinase). NNGH has been used to inhibit MMP-3 in a variety of studies. Inhibition of MMP-3 with NNGH significantly suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-KB, AP-1, and MAPK in LPS-stimulated microglia, suggesting a role for MMP-3 in neuroinflammation.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 15 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO
InChI
1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChI key
JIRXORZYIXSWOB-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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