PB28 dihydrochloride
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3179265 | Sigma-Aldrich | 5 MG | 1630 | 请咨询 |
结构式
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基本信息
| Linear Formula【线性分子式】 | C24H40Cl2N2O |
| Molecular weight | 443.49 |
| MDL number | MFCD06798349 |
| PubChem Substance ID【PubChem化学物质编号】 | 329820345 |
| NACRES | NA.77 |
| Application【应用】 | PB28 dihydrochloride has been used to test its inhibitory effect on potassium voltage-gated channel, shab-related subfamily, member 1, Kv2.1. |
| Biochem/physiol Actions【生化/生理作用】 | PB28, a cyclohexylpiperazine derivative, is a sigma 1 (σ1)-R antagonist. It elicits anti-tumor activity in breast, ovarian and colorectal cancer cell lines. Selective σ2 opioid receptor ligand; putative σ2 agonist |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: ~10 mg/mL at 60 ℃ |
| SMILES string | Cl[H].Cl[H].COc1cccc2C(CCCN3CCN(CC3)C4CCCCC4)CCCc12 |
| InChI | 1S/C24H38N2O.2ClH/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21;;/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3;2*1H |
| InChI key | DSRBJOQIBXACIV-UHFFFAOYSA-N |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |