脱氢枞酸

C₂₀H₂₈O₂

300.44

217-102-8

MFCD09839012

329824767

NA.25

脱氢枞酸(DHA 或 DAA)是一种具有生物活性的双萜类植物化学物质，存在于各种松属物种中。它是树脂酸和松香酸(AA)的衍生物。

Dehydroabietic acid has been used as a reference standard:

• to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)
• to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy
• to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

≥95% (LC/MS-ELSD)

solid

−20℃

CC(C)c1ccc2c(CC[C@H]3[C@@](C)(CCC[C@]23C)C(O)=O)c1

1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1

NFWKVWVWBFBAOV-MISYRCLQSA-N

GHS06,GHS09

Danger

H301 - H410

P273 - P301 + P310 + P330

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK 1