N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3168617 | Sigma-Aldrich | 5 MG | 2730 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C26H34N6O13 |
| Molecular weight | 638.58 |
| MDL number | MFCD00792707 |
| PubChem Substance ID【PubChem化学物质编号】 | 24890668 |
| NACRES | NA.32 |
| Amino Acid Sequence | NAc-Asp-Glu-Val-Asp-pNA |
| Application【应用】 | N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines. |
| Biochem/physiol Actions【生化/生理作用】 | Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O |
| InChI | 1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)/t16-,17-,18-,22-/m0/s1 |
| InChI key | GGXRLUDNGFFUKI-ORGXJRBJSA-N |
| Gene Information | human ... CASP3(836) |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |