N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3168619 | Sigma-Aldrich | 1 MG | 2730 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C30H34F3N5O13 |
| Molecular weight | 729.61 |
| MDL number | MFCD01310970 |
| PubChem Substance ID【PubChem化学物质编号】 | 329770614 |
| NACRES | NA.32 |
| Amino Acid Sequence | NAc-Asp-Glu-Val-Asp-AFC |
| Biochem/physiol Actions【生化/生理作用】 | A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin derivative has better membrane permeability than the 7-amido-4-methylcoumarin derivative (A1086). |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: 1 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1 |
| InChI | 1S/C30H34F3N5O13/c1-12(2)25(38-26(47)17(6-7-21(40)41)36-28(49)18(10-22(42)43)34-13(3)39)29(50)37-19(11-23(44)45)27(48)35-14-4-5-15-16(30(31,32)33)9-24(46)51-20(15)8-14/h4-5,8-9,12,17-19,25H,6-7,10-11H2,1-3H3,(H,34,39)(H,35,48)(H,36,49)(H,37,50)(H,38,47)(H,40,41)(H,42,43)(H,44,45)/t17-,18-,19-,25-/m0/s1 |
| InChI key | GZDRODOYEFEHGG-NUDCOPPTSA-N |
| Gene Information | human ... CASP3(836) |
| packaging【包装】 | Bottomless glass bottle. Contents are inside inserted fused cone. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |