硝呋莫司
Nifurtimox
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3175137 | Sigma-Aldrich | 25 MG | 6090 | 请咨询 |
| 3175137 | Sigma-Aldrich | 5 MG | 1660 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C10H13N3O5S |
| Molecular weight | 287.29 |
| EC number【EC 号】 | 245-531-0 |
| MDL number | MFCD00869254 |
| PubChem Substance ID【PubChem化学物质编号】 | 329818609 |
| NACRES | NA.77 |
| General description【一般描述】 | Nifurtimox acts as a hypoxia-activated cytotoxin, which specifically kills clonogenic tumor cells under hypoxic conditions. It is used to treat Chagas disease and African trypanosomiasis. Nifurtimox inhibits neuroblastoma and medulloblastoma cell growth. |
| Application【应用】 | Nifurtimox has been used in drug treatment in culture media. |
| Biochem/physiol Actions【生化/生理作用】 | Nifurtimox is a nitrofurane derivative used to treat diseases caused by trypanosomes. Nifurtimox was discovered empirically and its mechanism of action is unclear. It is believed that nifurtimox exerts its biological activity through the bioreduction of the nitro-group to a nitro-anion radical which undergoes redox-cycling with molecular oxygen. |
| Features and Benefits【特点和优势】 | This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | yellow to orange |
| solubility【溶解性】 | DMSO: ≥13 mg/mL |
| originator【创始人】 | Bayer |
| storage temp.【储存温度】 | room temp |
| SMILES string | CC1CS(=O)(=O)CCN1\N=C\c2ccc(o2)[N+]([O-])=O |
| InChI | 1S/C10H13N3O5S/c1-8-7-19(16,17)5-4-12(8)11-6-9-2-3-10(18-9)13(14)15/h2-3,6,8H,4-5,7H2,1H3/b11-6+ |
| InChI key | ARFHIAQFJWUCFH-IZZDOVSWSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |