NCX 4040
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3172784 | Sigma-Aldrich | 25 MG | 4160 | 请咨询 |
| 3172784 | Sigma-Aldrich | 5 MG | 1410 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C16H13NO7 |
| Molecular weight | 331.28 |
| MDL number | MFCD08062164 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825409 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. |
| Features and Benefits【特点和优势】 | This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 15 mg/mL (clear solution) |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(=O)Oc1ccccc1C(=O)Oc2ccc(CO[N+]([O-])=O)cc2 |
| InChI | 1S/C16H13NO7/c1-11(18)23-15-5-3-2-4-14(15)16(19)24-13-8-6-12(7-9-13)10-22-17(20)21/h2-9H,10H2,1H3 |
| InChI key | CTHNKWFUDCMLIQ-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS05,GHS07,GHS09 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H317 - H318 - H400 |
| Precautionary Statements | P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |