2'-脱氧鸟苷 一水合物

2′-deoxyguanosine monohydrate
CAS NO:312693-72-4
规格:99-100%
包装规格:1 G,100 MG,25 MG,5 G,1 G,250 MG,10g
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产品价格
产品编号品牌包装单位单价(元)现货
3121170Sigma-Aldrich1 G4070请咨询
3121170Sigma-Aldrich100 MG1330请咨询
3121170Sigma-Aldrich25 MG599请咨询
3121170Sigma-Aldrich5 G14360请咨询
3121171Sigma-Aldrich1 G10520请咨询
3121171Sigma-Aldrich100 MG1850请咨询
3121171Sigma-Aldrich250 MG3390请咨询
4018794Alfa Aesar10g9090请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C10H13N5O4 · H2O
Molecular weight
285.26
Beilstein
39814
MDL number
MFCD00150760
PubChem Substance ID【PubChem化学物质编号】
24894083
NACRES
NA.51
Application【应用】
2′-Deoxyguanosine monohydrate has been used as a nucleoside supplement:
  • to study its effect on mitochondrial DNA copy number in deoxyguanosine kinase (dguok) mutant zebrafish,
  • in tissue culture medium for deoxyribonucleotide triphosphate (dNTP) synthesis,
  • in RPMI (Roswell Park Memorial Institute)-1640 medium to eliminate the endogenous thymocytes

Biochem/physiol Actions【生化/生理作用】
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphorylation (kinases) forms deoxyguanosine triphosphate (dGTP) which is used by DNA polymerases and reverse transcriptases to synthesize DNA(s). Deoxyguanosine is the most electron-rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
synthetic (organic)
Assay【测定】
99-100%
form【形式】
powder
solubility【溶解性】
1 M NH4OH: 50 mg/mL, clear, colorless
SMILES string
O.NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](CO)O3)C(=O)N1
InChI
1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1
InChI key
LZSCQUCOIRGCEJ-FPKZOZHISA-N
packaging【包装】
1, 5 g in poly bottle
25, 100 mg in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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