产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3176074 | Sigma-Aldrich | 25 MG | 8810 | 请咨询 |
| 3176074 | Sigma-Aldrich | 5 MG | 3040 | 请咨询 |
| 4083777 | Sigma-Aldrich | 5 MG | 3540 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C15H16ClN3O3 |
| Molecular weight | 321.76 |
| MDL number | MFCD08276924 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724556 |
| NACRES | NA.77 |
| Application【应用】 | NSC 663284 has been used as a cell division cycle 25 (CDC25) inhibitor to study its effects on the level of kizuna (kiz) dephosphorylation. It has also been used as a control in horseradish peroxidase/phenol red based assay and resazurin-based redox assay. |
| Biochem/physiol Actions【生化/生理作用】 | NSC 663284 is a quinolinediones, which is involved in the inhibition of cell cycle progression at both G1 and G2/M phase. It is also involved in inhibiting the dephosphorylation and activation of cyclin-dependent kinases (Cdks) in vitro and in vivo. NSC 663284 stops the proliferation of various tumor cell lines. Potent, irreversible, cell permeable and mixed competitive CDC25 phosphatase family inhibitor |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | red |
| solubility【溶解性】 | DMSO: ≥10 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | ClC1=C(NCCN2CCOCC2)C(=O)c3ncccc3C1=O |
| InChI | 1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2 |
| InChI key | BMKPVDQDJQWBPD-UHFFFAOYSA-N |
| Gene Information | human ... CDC25B(994), DUSP3(1845), PTPN1(5770) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Flash Point(F)【闪点(F)】 | 470.1 °F |
| Flash Point(C)【闪点(C)】 | 243.4 ℃ |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |