10074-G5
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3115363 | Sigma-Aldrich | 25 MG | 4640 | 请咨询 |
| 3115363 | Sigma-Aldrich | 5 MG | 1570 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C18H12N4O3 |
| Molecular weight | 332.31 |
| MDL number | MFCD00576774 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799918 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | 10074-G5 is a c-Myc/Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4 (#F3680), specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM). It was discovered that 10074-G5 binds to a different specific binding site (region) of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | red |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| storage temp.【储存温度】 | room temp |
| SMILES string | [O-][N+](=O)c1ccc(Nc2ccccc2-c3ccccc3)c4nonc14 |
| InChI | 1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H |
| InChI key | KMJPYSQOCBYMCF-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |