N6-Cyclopentyladenosine

CAS NO:41552-82-3
规格:solid
包装规格:100 MG,25 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3171868Sigma-Aldrich100 MG2640请咨询
3171868Sigma-Aldrich25 MG1141请咨询
结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H21N5O4
Molecular weight
335.36
MDL number
MFCD00036845
PubChem Substance ID【PubChem化学物质编号】
24277686
NACRES
NA.77
Application【应用】
N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice.
N6-Cyclopentyladenosine has also been used to study its effect on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line.
Biochem/physiol Actions【生化/生理作用】
N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures.
N6-Cyclopentyladenosine also exhibits analgesic effect against acute, arthritis-induced and neuropathic pain.
Features and Benefits【特点和优势】
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Physical form【外形】
hygroscopic solid
产品性质
Quality Level【质量水平】
200
form【形式】
solid
color【颜色】
white to off-white
solubility【溶解性】
H2O: 1.7 mg/mL
0.1 M HCl: 12 mg/mL
DMSO: 23 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCC4)ncnc23
InChI
1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
InChI key
SQMWSBKSHWARHU-SDBHATRESA-N
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA3(140)
mouse ... Adora1(11539)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)
packaging【包装】
25 mg in poly bottle
100 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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