美普他酚 盐酸盐
Meptazinol hydrochloride
产品价格
| 产品编号 | 品牌 | 包装单位 | 单价(元) | 现货 |
| 3108784 | Sigma-Aldrich | 10 MG | 945 | 请咨询 |
| 4120135 | 100 MG | 2100 | 请咨询 |
结构式
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基本信息
| Empirical Formula【经验(实验)分子式】 | C15H23NO· HCl |
| Molecular weight | 269.81 |
| EC number【EC 号】 | 261-683-0 |
| MDL number | MFCD00941476 |
| PubChem Substance ID【PubChem化学物质编号】 | 329817952 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound. |
| Features and Benefits【特点和优势】 | This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | H2O: >10 mg/mL |
| originator【创始人】 | Wyeth |
| SMILES string | Cl.CCC1(CCCCN(C)C1)c2cccc(O)c2 |
| InChI | 1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H |
| InChI key | MPJUSISYVXABBH-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |