Oxatomide

CAS NO:60607-34-3
规格:≥99%
包装规格:10 MG
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产品价格
产品编号品牌包装单位单价(元)现货
3177997Sigma-Aldrich10 MG3050请咨询
基本信息
Empirical Formula【经验(实验)分子式】
C27H30N4O
Molecular weight
426.55
EC number【EC 号】
262-320-9
MDL number
MFCD00211147
PubChem Substance ID【PubChem化学物质编号】
24278615
NACRES
NA.77
General description【一般描述】
Oxatomide, a histamine H1-receptor antagonist, is bound at high levels to plasma proteins in human blood.
Biochem/physiol Actions【生化/生理作用】
Oxatomide, found in several antihistamines, can suppress mast cell degranulation. It can be used as an alternative to individuals with allergic rhinitis who do not or poorly respond to more established antihistamines. Oxatomide exhibits both antihistamine and anti-inflammatory properties. It exhibits therapeutic effects against asthma and vulvar lichen sclerosus.
Oxatomide is an anti-allergy compound. It suppresses platelet activating factor (PAF)-induced bronchoconstriction and inhibits leukotriene production.
Features and Benefits【特点和优势】
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥99%
color【颜色】
white
solubility【溶解性】
DMSO: soluble
ethanol: soluble
originator【创始人】
Johnson & Johnson
SMILES string
O=C1Nc2ccccc2N1CCCN3CCN(CC3)C(c4ccccc4)c5ccccc5
InChI
1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)
InChI key
BAINIUMDFURPJM-UHFFFAOYSA-N
Gene Information
human ... DRD3(1814)
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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